Phytochemicals, antioxidant, and antityrosinase activities of Achillea sivasica Celik and Akpulat

Haliloglu Y., ÖZEK T., Tekin M., GÖGER F., Baser K. H. C., ÖZEK G.

INTERNATIONAL JOURNAL OF FOOD PROPERTIES, cilt.20, 2017 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1080/10942912.2017.1308954
  • Dergi Adı: INTERNATIONAL JOURNAL OF FOOD PROPERTIES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Achillea sivasica, Antioxidant, Essential oil, Extract, Tyrosinase, RADICAL SCAVENGING ACTIVITY, ESSENTIAL OIL COMPOSITION, CHEMICAL-COMPOSITION, ANTIMICROBIAL ACTIVITY, MILLEFOLIUM L., PHENOLIC-COMPOUNDS, TRADITIONAL MEDICINE, DIFFERENT PARTS, FOLK MEDICINE, CONSTITUENTS
  • Anadolu Üniversitesi Adresli: Evet

Özet

The present study is the first report on essential oil (EO) composition, phytochemicals, and biological potential of Achillea sivasica tested against free radicals, oxidative damage, and tyrosinase enzyme. Gas-Chromatography Flame Ionization Detector (GC-FID) and gas chromatography/mass spectrometry (GC/MS) analyses revealed that beta-pinene (11.5%, 9.3%, and 6.7%), beta-pinene (7.0%, 3.0%, and 6.9%), 1,8-cineole (18.0%, 22.1%, and 6.7%), and camphor (7.6%, 4.1%, and 9.0%) were the major constituents in the EOs from the herb, flower, and leaves, respectively. Liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS) analysis of the extracts revealed the presence of caffeoylquinic acid derivatives, luteolin, apigenin, patuletin, isorhamnetin, cirsimaritin, and santin. The leaf extracts demonstrated strongest free radical scavenging, cupric reducing, lipid peroxidation inhibition, and antityrosinase activities.